Before going into the quotes...
I think part of the issue, Lokiare, is that you're expecting new genes to be created for old situations. For example, the yellow and blue snakes in the desert. Very quickly we'll see the trait of yellow become dominant. Like you said in this case, it's already there, so it's genetically very easy for it to become dominant. What's much more rare is for the snake to turn light brown if that trait never existed. Nevertheless, this process can happen. Before 1500 there were no records of white tigers... so where did they come from? Turns out a new gene was produced that inhibited the production of the striking orange coats!
http://www.livescience.com/34632-white-tiger-color-mystery-solved.htmlNeato!
So what I'm saying is that it's much easier to find situations where an old gene/protein simply takes up the function of the new requirement rather than a whole new protein being created, and as such it's much more difficult to study. Carrying on...
Lokiare wrote:
It was an example for people to wrap their minds around how proteins work. Small changes destroy the usefulness of a protein, but you can have huge changes (25-500 specific base pair changes) that make a protein that does nearly the exact same thing.
That's what I mean. The sentence you provided can be warped around a bunch of times to say the same things in different ways. However, when you further break it down into the basic language, you'll find that you can say lots of different things to:
Today, the heavens are azure.
(adverb), the (noun) (verb "to be") (adjective).
Oddly, the cow is flumoxed.
The result? New information!
Quote:
This is an example of the
homunculus fallacy. Its fine to say 'we don't know how that happened', its not fine to base other knowledge and theories on your assumption of how something works, as they do often in Evolution.
That's not really how the Homunculus fallacy works. There is no infinite regress here, which is the basis of the homunculus fallacy. It would be a homunculus fallacy if we said that proteins require a change in the DNA which requires a change in the proteins, because then it would infinitely regress. However, even if we assume that there is a regress here (basing theories on a bad theory means that the new theory is also bad and will require a new theory), then the argument is still invalid, as it makes an assumption that the new theory will be bad. I think these discussions are evidence that non-evolutionary models are always considered and tested in addition to standard tests. However, these other models are not able to stand up to the same amount of scrutiny as the current model. Both models collapse at the end (only because we still have more to learn), but as the evolutionary model can withstand greater scrutiny to further along the line, it makes logical sense that it is closer to the "true" final answer.
By example, if an earthquake happens, and I say it happened because of tectonic plates and you say it happened because of a flying saucer, both hypothesis can be tested, and both will eventually fail. The difference is that yours will fail much sooner (no laser beams detected, etc.), while mine will fail only once we start trying to locate the exact rock that broke that triggered the cascade of tectonic pressure release. Similarily, non-evolutionary models collapse sooner under scientific scrutiny than evolutionary models - but the evolutionary model does still collapse if you look far enough, such as what you are doing. That does not mean that the theory is wrong, only that there continue to be portions of the theory that need to be filled in.
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The problem here is that these parts of the theory have been proven false. Whereas Newton's model wasn't found to be false, only imprecise. In other words if they showed that his model didn't work at all, then they would have thrown it out. If we found even a few instances where these evolutionary theory models worked and had proof, I'd have no problem including them into the 'maybe this is how it is' category. Unfortunately its base speculation at this point.
Newton's model is entirely false, sorry to say. There is no gravitational constant. In fact, in Relativistic models, there is no gravity - just a curvature of space. Objects of mass do not "pull" on each other. If I fire a rocket directly perpendicular to Earth and start falling towards it, it won't be because Earth is pulling me, or because I fired rockets in the wrong direction... my space-time momentum literally makes a straight line into a visually curved one.
Newton's theory is entirely false, not just imprecise. However, even though it is false, it is still very useful for most day to day situations, and Force is much easier to calculate than Tensors (space-time points and movements). As such, we still use it.
Evolutionary models may not be perfect, but they describe what we see so well that until a better model comes along, we might as well use it.
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Yes. Unfortunately duplicate genes produce many problems in an organism including cancer, toxins, overproduction of enzymes, diseases, increased cell size, reduced production within a cell, etc...etc...
As I said in another post proteins if changed even a small amount cease to function and can even cause negative side effects. So in order for a gene to mutate into another useful gene for the production of proteins very specific changes have to take place. There are a finite number of combinations of proteins that actually work within an organism due to the traits of the organism. What really throws this out though is that
some genes code for multiple proteins which means one change in them could stop production of 3-4 other proteins that are needed, and duplication could cause massive overdoses or negative changes in an organism. The only way it would work is if it was duplicated and rendered inoperable and neutral at the same time and then you have to have a mated organism with the same exact change in order to keep the change. We are talking insane odds mathematically and then when you take into account that natural selection is just as likely to kill off neutral mutations as positive or negative ones and the fact that all of this has to happen inside the reproductive cells (of which most female animals are born with them meaning a very limited time for mutations when formed) it gets just flat out insane.
Gene duplication experiments have been done over and over and over and they always end in failure because gene duplication in mammals is deadly. In other words even if lower forms of life evolved through gene duplication (which I've shown above that its unlikely) mammals would never have evolved.
Unfortunately, science disagrees with you:
http://www.sciencedirect.com/science/article/pii/S0169534703000338 - Evolution by gene duplication: an update
http://www.biomedcentral.com/1471-2148/7/2 - Inventing an arsenal: adaptive evolution and neofunctionalization of snake venom phospholipase A2 genes
http://www.nature.com/nrg/journal/v9/n12/full/nrg2482.html - How duplicated genes find new functions
http://www.annualreviews.org/doi/abs/10.1146/annurev.genet.38.072902.092831?journalCode=genet& - DUPLICATION AND DIVERGENCE: The Evolution of New Genes and Old Ideas
http://www.nature.com/nature/journal/v428/n6983/full/nature02424.html - Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1460548/ - How keeping around junk DNA through gene duplication helps increase odds of beneficial new traits
(there's lots more if you do a Google search, though admittedly they tend to be locked up in paid-for peer-review journals)
That said, I was especially tempted to look at the last one on that list.
Gene duplication is viable, even if it results in a greater risk of deleterious mutations, due to the greater chance and probabilities (far higher than the numbers you've quoted) of hitting beneficial new traits.