Eclipse Phase is a science fiction horror[1] role-playing game with transhumanist themes.[2] Futurist Anders Sandberg noted its difference from GURPS Transhuman Space was its emphasis on posthuman (rather than transhuman) characters.[3] Originally published by Catalyst Game Labs,[4] Eclipse Phase is now published by the game's creators, Posthuman Studios and is released under a Creative Commons license.[5][6][7][8] In 2010, it won the 36th Annual Origins award for Best Roleplaying Game.[9] It also won three 2010 ENnie awards: Gold for Best Writing, Silver for Best Cover Art, and Silver for Product of the Year.[10]

Eclipse Phase is a post-apocalyptic game of conspiracy and horror.[11] The setting takes place after a World War III project to create artificial intelligence went rogue under the influence of an extraterrestrial entity known as the "Exsurgent" (best described as an organic computer virus with the capacity to infect both machines and animals with sapient qualities), resulting in the deaths of over 90% of the inhabitants of Earth.

Earth is subsequently abandoned, and existing colonies throughout the Solar System are expanded to accommodate the refugees. The setting explores a spectrum of socioeconomic systems in each of these colonies:

-A capitalist/republican system continues in the Inner System (Mars, the Moon, and Mercury), under the Planetary Consortium, a corporate body which allows the election of representatives but whose shareholders are nominally most powerful.
-An Extropian/Propertarian system is established in the Asteroid Belt.
-A military oligarchy rules the moons around Jupiter.
-An alliance of Scandinavia-style social democracy and Collectivist anarchism are dominant in the Outer System.
-From there, the setting explores various scientific advances, extrapolated far into the future. Nanotechnology, terraforming, Zero-G living, upgrading animal sapience, and reputation systems are all used as plot points and background.

With all of this, the game encourages players to confront existential threats like aliens, weapons of mass destruction, Exsurgent Virus outbreaks, and political unrest.

I've considered running a SWRPG game here. But i have basically no experience with the ruleset.